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Deed of Non-Competition - Quintiles Transnational Corp. and David F. White

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                           DEED OF NON-COMPETITION

                                   BETWEEN

                        QUINTILES TRANSNATIONAL CORP.

                                     AND

                               DAVID F. WHITE

                              29 NOVEMBER 1996
<PAGE>   2

                                     INDEX



  Clause                                                                  Page
  ------                                                                  ----


   1. Certain Definitions..............................................     3

            1.1    Certain Definitions.................................     3

   2. Non-competition and Non-solicitation Covenants...................     3

            2.1    General.............................................     3

            2.2    Non-Competition.....................................     3

            2.3    Holding of Shares or Securities.....................     5

            2.4    Nondisclosure.......................................     5

            2.5    Geographical Restriction............................     5

            2.6    Non-Competition Period..............................     6

            2.7    Remedies............................................     6

            2.8    Other Agreements....................................     6

   3. General Provisions...............................................     6

            3.1    Notices.............................................     6

            3.2    Variation...........................................     7

            3.3    Entire Agreement....................................     7

            3.4    Assignment..........................................     8

            3.5    Law and Jurisdiction................................     9


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<PAGE>   3

THIS NON-COMPETE AGREEMENT dated 29 November 1996 is executed as a Deed and
is made

BETWEEN

(1)       QUINTILES TRANSNATIONAL CORP., a corporation incorporated under the
          laws of North Carolina, U.S.A. (the "Purchaser"); and

(2)       DAVID F. WHITE, an individual residing at Little Barlows, Frieth,
          Henley on Thames, Oxon, RG9 6PR (the "Vendor").

WHEREAS:

(A)      Concurrently with the execution of this Agreement, the Purchaser, the
         Vendor and others are consummating certain transactions under a Share 
         Exchange Agreement ("the Share Exchange Agreement") pursuant to which 
         the Vendor and other vendors are exchanging their shares of Innovex
         Limited ("Innovex") for shares of Quintiles Transnational Corp.

(B)      The Vendor is entering into this Agreement as a condition precedent to
         completion under the Share Exchange Agreement.

(C)      Upon completion of the share exchange pursuant to the Share Exchange
         Agreement, Vendor will own approximately 39,904 shares of the
         outstanding common stock of the Purchaser.

NOW THIS DEED WITNESSETH as follows:

                           1.  CERTAIN DEFINITIONS

1.1      Certain Definitions.  In this Agreement the following words and
         expressions shall have the meanings respectively ascribed to them:

         "Affiliates" shall mean: (i) the Purchaser; (ii) any Purchaser
         subsidiary or related entity (including without limitation Innovex and
         its subsidiaries); and (iii) any entity directly or indirectly
         beneficially owned or controlled in whole or part by the Purchaser
         or any Purchaser subsidiary or related entity, in each case as
         existing at or prior to the date of termination of Vendor's
         employment.

             2.  NON-COMPETITION AND NON-SOLICITATION COVENANTS

2.1      General.  In consideration of the Purchaser agreeing to complete the
         Share Exchange Agreement, during the Vendor's employment with the
         Purchaser and the Non-Competition Period (as defined in Section 2.6):

2.2      Non-Competition.  The Vendor shall not, either alone or jointly with
         another or others, whether as principal, agent, director, shareholder,
         independent contractor, officer, employee or in any other capacity,
         whether directly or indirectly, and whether for his own benefit or
         that of others:



                                      3
<PAGE>   4


(a)    be engaged or have an economic interest in any business which competes
with any business carried on or engaged in by the Purchaser or any of its      
Affiliates at or before (provided such business has not been terminated or
abandoned by Purchaser or such Affiliate) the date of termination of Vendor's
employment, including without limitation Related Activities (as defined below)
(hereinafter, a "Competitive Business");

(b)    solicit or endeavor to solicit on behalf of a Competitive
Business, from or with any person or entity:

        (i)     who or which was a customer of the Purchaser or any of its
Affiliates at any time during the period of twelve (12) months preceding the
date of the termination of the Vendor's employment;

        (ii)    who or which the Vendor or someone for whom he was directly
responsible solicited, negotiated, contracted, serviced, advised or had contact
with on the Purchaser's or any of its Affiliates' behalf; or

        (iii)   to whom the Purchaser or any of its Affiliates had made
proposals to do business at any time during the period of twelve (12) months
preceding the date of the termination of the employment;

(c)    deal, do business or endeavor to deal or do business for a Competitive  
Business from or with any person or entity:          

        (i)     who or which was a customer of the Purchaser or any of its
Affiliates at any time during the twelve (12) months preceding the date of the
termination of the employment;

        (ii)    who or which the Vendor or someone for whom he was directly
responsible solicited, negotiated, contracted, serviced, advised or had contact
with on the Purchaser's or any of its Affiliates' behalf; or

        (iii)   to whom the Purchaser or any of its Affiliates had made
proposals to do business at any time during the period of twelve (12) months
preceding the date of the termination of the employment;

(d)    without the written permission of the Board of the Purchaser (such
permission not to be unreasonably withheld or delayed and in particular such   
permission will not be withheld if the Purchaser considers that the Vendor has
neither a personal influence with clients nor is in possession of confidential
information) offer employment to or otherwise solicit for employment the
services of any individual who was an employee or director of the Purchaser or
any of its Affiliates during the period of twelve (12) months preceding the
date of termination of employment whether or not such persons would commit any
breach of his contract of employment with the Purchaser or any of its
Affiliates by reason of his leaving service; or

(e)    directly or indirectly take any action which is intended to be  
materially detrimental or otherwise intended to be adverse to the Purchaser's
and/or any of its Affiliates'



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<PAGE>   5

    goodwill, name, business relations, prospects and operations.

    Notwithstanding anything in this Agreement to the contrary, the following
    activities will not be deemed to contravene the provisions of this
    Agreement:

        (i)     Owning, operating, controlling or serving as a director,
    officer or employee of or consultant to any company the principal business
    of which is manufacturing, distributing, marketing and/or selling
    pharmaceutical products the rights to which are owned by or licensed to
    such company; provided that the amount of the consolidated revenues of such
    company in any year derived from operations (as defined below, "Related
    Activities") involving providing, on a contract, for hire, or similar basis
    (i) drug development services, (ii) pharmaceutical or clinical research
    services, (iii) pharmaceutical sales or marketing services, (iv) health
    information management services, and/or (v) any other activity which       
    constitutes a significant part of the business of the Purchaser (in the
    case of subparagraph (v), at or before the date of termination of Vendor's
    employment) will not exceed the greater of five percent (5%) of
    consolidated revenues or five percent (5%) of consolidated expenses of such
    company; provided further that Vendor shall have no direct involvement in
    such Related Activities as a director, officer, employee, consultant or
    otherwise; provided further, it is agreed that Related Activities are
    intended to be limited to activities which are incidental to the operations
    of a pharmaceutical business and are not, without limiting the foregoing,
    any activities dedicated primarily to a Competitive Business or the purpose
    of drug development, marketing, sales services, or health benefit analysis
    of the products or potential products of third parties.

        (ii)    the provision of executive search consulting services so long

        as such services are not provided to an entity engaged in Related
        Activities; and

        (iii)   the provision of financial consulting services so long as such
        services are not provided to an entity engaged in Related Activities.

2.3 Holding of Shares or Securities.  Section 2.2 shall not prohibit the
    holding (directly or through nominees or otherwise) of shares or other     
    securities of another company which are listed or traded on any recognized
    stock exchange being a holding (which phrase shall include any interest in
    any such holding) entitling the holder to no more than two and one half
    percent (2.5%) of the voting power of such body corporate.

2.4 Nondisclosure.  The Vendor shall not either before or after the
    termination of his employment disclose to any person or persons any
    confidential information in relation to the affairs of the Purchaser or any
    of its Affiliates or any client or customer thereof which he has become
    or may have become possessed whilst in the service of the Purchaser except
    in the proper course of his duties as an officer, director or employee of
    the Purchaser or as authorized by the Board or as ordered by a Court of
    competent jurisdiction or pursuant to other governmental process.

2.5 Geographical Restriction.  The restrictions set forth in Sections
    2.2(a) apply to the following geographical areas: the United Kingdom, the  
    Federal Republic of Germany and the United States of America, including the
    territories and possessions thereof.



                                      5
<PAGE>   6


2.6 Non-Competition Period.  As used in this Agreement "Non-Competition
    Period" means the eighteen (18) month period following the termination of
    Vendor's employment, (irrespective of the circumstances of such
    termination, except that the final six months of any garden leave period
    shall run concurrently with the first six months of the Non-Competition
    Period), except that for purposes of the restrictions set forth in Sections
    2.2(b) and 2.2(c) (regarding solicitation, etc.), "Non-Competition Period"
    shall mean the twenty-four (24) month period following the termination of
    Vendor's employment (irrespective of the circumstances of such termination).

2.7 Remedies.  Vendor acknowledges and agrees that Vendor's failure to
    abide by the provisions of this Agreement would cause irreparable harm to
    the Purchaser and/or its Affiliates for which legal remedies would be
    inadequate. Therefore, in addition to any legal or other relief to which
    the Purchaser and/or its Affiliates may be entitled by virtue of
    Vendor's failure to abide by these provisions: (i) the Purchaser may seek
    legal and equitable relief, including but not limited to preliminary and
    permanent injunctive relief, for Vendor's actual or threatened failure to
    abide by these provisions; (ii) Vendor will, upon final judicial
    determination that Vendor has breached the terms of this Agreement,
    indemnify the Purchaser and/or its Affiliates for all expenses (including
    legal fees) in seeking to enforce these provisions; and (iii) if, as a
    result of Vendor's failure to abide by the provisions, any commission or
    fee becomes payable to Vendor or to any person, corporation or other entity
    with which Vendor has become employed or otherwise associated, Vendor shall
    pay the Purchaser or cause the person, corporation or other entity with
    whom he has become employed or otherwise associated to pay the Purchaser an
    amount equal to such commission or fee.

2.8 Other Agreements.  Nothing in this Agreement shall terminate, revoke
    or diminish Vendor's obligations or the Purchaser's and/or its Affiliates'
    rights and remedies under law or under Vendor's existing service agreement 
    and the Share Exchange Agreement relating to trade secrets, confidential
    information, non-competition and intellectual property.

                            3. GENERAL PROVISIONS

3.1 Notices.  All notices, demands, requests, or other communications which
    may be or are required to be given, served, or sent by any party to any
    other party pursuant to this Agreement shall be in writing and shall be    
    hand delivered, sent by overnight courier or mailed by first-class
    registered post, postage prepaid, return receipt requested or transmitted
    by telegram, telecopy or telex, addressed as follows:

    (a)  If to the Purchaser:           
                                        
         Quintiles Transnational Corp.  
         4709 Creekstone Drive          
         Riverbirch Building, Suite 300 
         Durham, North Carolina         
         U.S.A. 27703                 
         Attention:  Gregory D. Porter
         Fax: 919-941-2090             

                                      6
<PAGE>   7

            with a copy which shall not constitute notice to:         
                                                                      
            Smith, Anderson, Blount, Dorsett, Mitchell & Jernigan L.L.P
            2500 First Union Capital Center                           
            Raleigh, North Carolina                                   
            U.S.A. 27601                                              
                                                                      
            Attention:  Gerald F. Roach                               
                                                                      
            Fax: 919-821-6800                                         
                                                                      
                                                                      
                                                                      
       (b)  If to the Vendor:                                         
                                                                      
            David F. White                                            
            Little Barlows, Frieth                                    
            Henley on Thames                                          
            Oxon, RG9 6PR                                             
                                                                      
            With a copy which shall not constitute notice to:         






            Attention:

            Fax:


       Each party may designate by notice in writing a new address to which
       any notice, demand, request or communication may thereafter be so given,
       served or sent.  Each notice, demand, request, or communication which
       shall be hand delivered, sent, mailed, telecopied or telexed in the
       manner described above, or which shall be delivered to a telegraph
       company, shall be deemed sufficiently given, served, sent, received or
       delivered for all purposes at such time as it is delivered to the
       addressee (with the return receipt, the delivery receipt, or (with
       respect to a telecopy or telex) the answerback being deemed conclusive,
       but not exclusive, evidence of such delivery) or at such time as
       delivery is refused by the addressee upon presentation.

3.2    Variation.  No variation of this Agreement shall be valid or effective
       unless made by one or more instruments in writing signed by all of the
       parties hereto.

3.3    Entire Agreement.  Except as expressly provided in this Agreement, this
       Agreement: (i) supersedes and cancels all other understandings and
       agreements, oral or written, with respect to Vendor's obligations with
       respect to non-competition which Vendor has

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       executed in the past; (ii) supersedes all other understandings and
       agreements, oral or written, between the parties with respect to the
       subject matter of this Agreement; and (iii) constitutes the sole
       agreement between the parties with respect to the matters covered.  No  
       change or modification of this Agreement shall be valid or binding
       upon the parties unless such change or modification is in writing and is
       signed by the parties.


3.4    Assignment.  Neither of the parties hereto shall assign or otherwise
       deal with any of its right, title or interest in this Agreement without
       the prior written consent of the other party to this Agreement, which
       consent may be withheld in such party's absolute discretion, provided,
       however, that the Purchaser may in its absolute discretion assign all or
       any of its right title and interest in this Agreement to a an Affiliate
       or to a subsequent purchaser of all of the share capital of the Company
       or all or substantially all of the assets of the Company.

                                      8

<PAGE>   9


3.5    Law and Jurisdiction.  This Agreement shall be governed by and
       construed in accordance with English law and the parties irrevocably
       submit to the non-exclusive jurisdiction of the High Court of Justice
       in London for all purposes connected with it.

IN WITNESS whereof this Agreement has been executed and unconditionally
delivered as a Deed the day and year first-above written.



Signed and delivered as a Deed          )
by Quintiles Transitional Corp.         )
by its duly authorized                  )
Vice President, Rachel R. Selisker,     )
and by its duly authorized              )
Secretary, Gregory D. Porter            )


/s/ Rachel R. Selisker
- ------------------------------
Rachel R. Selisker
Vice President



/s/ Gregory D. Porter
- ------------------------------
Gregory D. Porter
Secretary


Signed and delivered as a Deed          )
by David F. White                       )     /s/ David F. White


in the presence of:


Name: P. Knott
     -----------------------------      )
Address: The Gables                     )
         -------------------------      )
         Elvendon Road, Gorine-on-      )
         -------------------------      )
         Thames, Oxon RG8 ODT           )
         -------------------------      )
Occupation: Director                    )
            ----------------------      )
                                       
                                       
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