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Patent Cross-License Agreement - Terragen Discovery Inc. and Diversa Corp.

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                        PATENT CROSS-LICENSE AGREEMENT

          This agreement ("Agreement"), effective as of the 18/th/ day of
November, 1999 ("Effective Date"), is made by and between Terragen Discovery
Inc., a British Columbia corporation ("Terragen"), having its principal place of
business at Suite 300-2386 East Mall - UBC, Vancouver, British Columbia, Canada
V6T 1Z3, and Diversa Corporation, a Delaware corporation ("Diversa"), having its
principal place of business at 10665 Sorrento Valley Road, San Diego, California
92121.

          Whereas, Terragen is the owner of [*****] Terragen Patent Rights (as
hereinafter defined), and Diversa is the owner of [*****] Diversa Patent Rights
(as hereinafter defined), both embodying technologies applicable in discovery of
multi-gene pathways and biomolecules of interest;

          Whereas, each party is desirous of acquiring certain rights under the
other party's patent rights to use the other party's technology for the [*****];
and

          Whereas, each party is willing to grant the other party such rights in
accordance with the terms and conditions set forth in this Agreement.

          Now, Therefore, in consideration of the foregoing recitals and the
mutual covenants and conditions set forth herein, Terragen and Diversa hereby
agree as follows:

                                   ARTICLE 1

                                  DEFINITIONS

          "[*****]" shall mean a [*****]

          "Diversa Patent Rights" shall mean patents and patent applications set
forth in Exhibit A hereto, and all continuations-in-part, continuations,
divisionals, reissues, re-examinations or extensions thereof, and any foreign
patents and patent applications corresponding thereto. Diversa may modify
Exhibit A from time to time by providing written notice to Terragen to include
patents and patent applications that may be required in order for Terragen to
practice Diversa Patent Rights or Terragen Patent Rights.

          "Diversa Products" shall refer to all products made, use, sold,
offered for sale or imported by Diversa that but for the licenses granted herein
would infringe Terragen Patent Rights.

          "Field 1" shall mean small molecules for pharmaceutical applications.

          "Field 2" shall mean all fields except Field 1.

          "Patent Rights" shall refer to Terragen Patent Rights and Diversa
Patent Rights.

          "[*****]" shall mean a [*****].

           "Terragen Patent Rights" shall mean patents and patent applications
set forth in Exhibit B hereto, and all continuations-in-part, continuations,
divisionals, reissues, re-examinations or extensions thereof, and any foreign
patents and patent applications corresponding thereto, as well as any patents
and patent applications necessary to practice microdroplet screening
technologies as described in the patents and patent applications in Exhibit B.
Terragen may modify Exhibit B from time to time by providing written

                                      1.       *Confidential Treatment Requested
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notice to Diversa to include patents and patent applications that may be
required in order for Diversa to practice Diversa Patent Rights or Terragen
Patent Rights.

           "Terragen Products" shall refer to small molecules generated by the
expression of partial, complete or hybrid gene pathways made, used, sold,
offered for sale or imported by Terragen that but for the license granted herein
would infringe Diversa Patent Rights. It is understood that small molecules do
not include proteins or nucleic acids.

           "Valid Claim" shall mean: (i) a claim of an issued and unexpired
patent that has not been revoked or held unenforceable or invalid by a decision
of a court or other governmental body of competent jurisdiction, unappealable or
unappealed within the time allowed for appeal, and which has not been
statutorally disclaimed; or (ii) a claim included in a pending patent
application that is actively prosecuted and which has not been cancelled,
withdrawn, finally determined to be unallowable by the applicable governmental
body pursuant to an unappealable decision and/or abandoned in accordance with
the terms hereof.

                                   ARTICLE 2

                                 LICENSE GRANT

     2.1   Terragen License Grant. Subject to the terms and conditions set forth
herein, Terragen hereby grants to Diversa the following:

           (a)  a co-exclusive, non-royalty bearing, worldwide, [*****] license
under Terragen Patent Rights to [*****] in Field 2. This license shall [*****]
to the [*****]. During the term of the license, Terragen will [*****] to [*****]
under [*****] in Field 2 to [*****].

           (b)  a non-exclusive, non-royalty bearing, non-sublicenseable,
worldwide license under Terragen Patent Rights to [*****] in Field 1, provided
that [*****] from the Effective Date, the license under this subparagraph shall
[*****]. This license shall [*****].

     2.2   Diversa License Grant.  Subject to the terms and conditions set forth
herein, Diversa hereby grants to Terragen the following:

           (a)  a non-exclusive, non-royalty bearing, worldwide, [*****] license
under Diversa Patent Rights to [*****] in Field 1.

     2.3   License Limitations.

           (a)  Diversa agrees that it will not [*****] in [*****] of Diversa
Products in Field [*****] for a period of [*****] from the Effective Date.

           (b)  Terragen agrees that it will not [*****] in the [*****] and/or
[*****] of Terragen Products for a period of [*****] from the Effective Date.

                                   ARTICLE 3

                                 CONSIDERATION

     3.1  Fees.  In consideration of the licenses granted to Diversa by Terragen
under the terms of this Agreement, Diversa has granted the license referred to
in Section 2.2 and will pay Terragen the following:

           (a)  [*****] within [*****] of the Effective Date:

                                      2.       *Confidential Treatment Requested
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          (b)  an annual maintenance fee of [*****] within [*****] of [*****] of
the Effective Date until [*****] included in the [*****] unless the Agreement is
terminated earlier pursuant to Article 7 below.

                                   ARTICLE 4

                             INTELLECTUAL PROPERTY

     4.1  Except as permitted below, in further consideration of the licenses
granted under the terms of this Agreement, Terragen will not institute a legal
action challenging the validity and/or enforceability of Diversa Patent Rights,
and Diversa will not institute any legal action challenging the validity and/or
enforceability of Terragen Patent Rights, in each case, during the term of this
Agreement. "Legal action challenging the validity and/or enforceability of
Diversa Patent Rights/Terragen Patent Rights" shall include, but is not limited
to, pre-grant or post-grant opposition proceedings, utility suits, reexamination
proceedings, declaratory judgement actions, and civil actions under 35 U.S.C.
(S) 291 (interfering patents).

     4.2  Except as permitted below, in further consideration of the licenses
granted under the terms of this Agreement, neither party shall take any action
to hinder or delay prosecution of patents or patent applications owned or
controlled by the other party and within the scope of Patent Rights without the
prior written consent of said other party during the term of this Agreement.
"Action taken to hinder or delay prosecution of patent applications" shall
include, but is not limited to, formal or informal protests and third-party
observations.

     4.3  Upon the execution of this Agreement, a party who has brought a
pending legal action challenging the validity or enforceability of any patent or
patent application owned or controlled by the other party and within the scope
of Patent Rights, shall take appropriate steps to terminate said pending legal
action.

     4.4  Notwithstanding the provisions of sections 4.1 and 4.2, a party may
present and prosecute one or more claims that are directed to the same
patentable invention as any claim(s) of the other party. Claims may be presented
to satisfy the provisions of 35 U.S.C. (S) 135(b) or otherwise, e.g., at the
request of an Examiner.

     4.5  Notwithstanding the provisions of sections 4.1 and 4.2, in the event a
patent infringement action is brought against a party to this Agreement, the
party charged with infringement shall be permitted to raise all defenses
permitted by law, including invalidity or unenforceability of the patent
asserted against the party charged with infringement.

     4.6  Notwithstanding the provisions of sections 4.1 and 4.2, nothing in
this agreement shall prevent a party from disclosing material information to the
Patent and Trademark Office to satisfy the duty of disclosure under 37 C.F.R.
(S) 1.56.

     4.7  If the United States Patent and Trademark Office declares an
interference proceeding involving Terragen Patent Rights and Diversa Patent
Rights, the parties will negotiate a settlement of such an interference in good
faith. These negotiations will address all priority and non-priority issues that
could have been brought in the interference.

     4.8  Infringement by Third Parties.

          (a)  In the event that either party determines that a third party is
making, using, or selling a product that may infringe a patent included in the
Patent Rights, it will promptly notify the other party in writing.

          (b)  Except as provided under Section 4.8(c), the party in whose name
the allegedly infringed Patent Rights are registered shall be solely responsible
for determining whether to bring suit

                                      3.       *Confidential Treatment Requested
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against such alleged infringer and controlling such suit, and the other party
shall take all reasonable steps to assist in such suit, provided that the
expenses of the other party are paid by the controlling party.

          (c)  If the matter involves an alleged infringement of the Terragen
Patent Rights in Field 2, then Terragen shall be initially responsible for
determining whether to bring suit against such alleged infringer. In the event
Terragen decides to bring suit, it shall give prompt written notice to Diversa
of that fact, and Diversa shall take all reasonable steps to assist Terragen in
such suit. Terragen shall be entitled to all amounts recovered in such suit
(other than amount to be paid to Diversa, should Diversa elect to join in such
suit as provided for herein), except that Diversa shall have the right to elect
to pay up to fifty percent (50%) of the litigation costs and receive a
percentage of any recovery equal to the percentage of total litigation costs,
including reasonable attorneys' fees, paid by Diversa. Diversa must make such
election within sixty (60) days of its receipt of Terragen's notice that it has
decided to bring suit. Diversa shall also have the right to be represented by
separate counsel in any such suit. Terragen shall have control over any such
suit, and decisions as to settlement, methods and/or terms and conditions for
resolving the suit shall be made by Terragen after good faith consultation with
Diversa. Upon the earlier of (i) Terragen's election not to bring a suit against
the alleged infringer, as indicated by prompt written notice to Diversa, or (ii)
180 days after Terragen has notice of such alleged infringement if Terragen has
not been able to cause the alleged infringer to cease infringement, Diversa
shall have the right, at its option, to commence such action at its own cost and
expense, in which case Diversa shall have control over such suit and be entitled
to all amounts recovered in such action, subject to payment of any costs of
Terragen in assisting in such suit. Subject to the right to receive payment for
its costs out of amounts recovered as aforesaid, Terragen shall take all
reasonable steps to assist Diversa in such suit.

     4.9   Parties to Maintain Patent Rights. Each party shall have the
obligation and be responsible at its own cost and expense for maintaining and
extending those Patent Rights under its control for the term of this License.
Subject to Section 4.10, each party shall use good faith efforts to prosecute,
issue and maintain all Patent Rights.

     4.10  Notice of Patent Lapse of Patent Rights. In the event that a party
elects to abandon any of the Patent Rights under its control, it shall promptly
advise the other party of the grant, lapse, nullification, revocation,
surrender, or invalidation of any such Patent Rights at least in advance of any
abandonment to enable the other party (the "Assuming Party") to assume that
prosecution, at the Assuming Party's expense, should the Assuming Party not
agree to such abandonment.

                                   ARTICLE 5

                 LIMITED WARRANTIES/INDEMNIFICATION/LITIGATION

     5.1   Limited Warranty.  Each party warrants to the other that it has the
full right and power to make the representations and agreements set forth
herein. Terragen warrants that Exhibit B lists patent applications filed on or
before the Effective Date owned by Terragen, and Diversa warrants that Exhibit A
lists patent applications filed on or before the Effective Date owned by
Diversa.

     5.2   No Other Warranties by Terragen. WITH RESPECT TO TERRAGEN PATENT
RIGHTS AND TERRAGEN TECHNOLOGY, TERRAGEN EXPRESSLY DISCLAIMS ALL WARRANTIES OF
ANY KIND AND MAKES NO EXPRESS OR IMPLIED WARRANTIES WHATSOEVER INCLUDING,
WITHOUT LIMITATION, IMPLIED WARRANTIES OF MERCHANTABILITY, SATISFACTORY QUALITY
OR FITNESS FOR A PARTICULAR PURPOSE, EXCEPT AS EXPRESSLY PROVIDED IN PARAGRAPH
5.1 ABOVE. TERRAGEN EXPRESSLY DISCLAIMS ALL WARRANTIES AS TO THE VALIDITY OR
SCOPE OF TERRAGEN PATENT RIGHTS, OR THAT THE TERRAGEN TECHNOLOGY WILL BE FREE
FROM INFRINGEMENT OF PATENTS OR PROPRIETARY RIGHTS OF THIRD PARTIES, OR THAT NO
THIRD PARTIES ARE IN ANY WAY INFRINGING TERRAGEN PATENT RIGHTS. In no event
shall Terragen be liable for any consequential, indirect, or incidental damages.
Further, Diversa shall make no statements, representations or warranties
whatsoever to any third party which are inconsistent with this disclaimer by
Terragen.

                                      4.       *Confidential Treatment Requested
<PAGE>

     5.3   No Other Warranties by Diversa. WITH RESPECT TO DIVERSA PATENT RIGHTS
AND DIVERSA TECHNOLOGY, DIVERSA EXPRESSLY DISCLAIMS ALL WARRANTIES OF ANY KIND
AND MAKES NO EXPRESS OR IMPLIED WARRANTIES WHATSOEVER INCLUDING, WITHOUT
LIMITATION, IMPLIED WARRANTIES OF MERCHANTABILITY, SATISFACTORY QUALITY OR
FITNESS FOR A PARTICULAR PURPOSE, EXCEPT AS EXPRESSLY PROVIDED IN PARAGRAPH 5.1
ABOVE. DIVERSA EXPRESSLY DISCLAIMS ALL WARRANTIES AS TO THE VALIDITY OR SCOPE OF
DIVERSA PATENT RIGHTS, OR THAT THE DIVERSA TECHNOLOGY WILL BE FREE FROM
INFRINGEMENT OF PATENTS OR PROPRIETARY RIGHTS OF THIRD PARTIES, OR THAT NO THIRD
PARTIES ARE IN ANY WAY INFRINGING DIVERSA

PATENT RIGHTS. In no event shall Diversa be liable for any consequential,
indirect, or incidental damages. Further, Terragen shall make no statements,
representations or warranties whatsoever to any third party which are
inconsistent with this disclaimer by Diversa.

     5.4  Infringement Litigation. Each party shall notify the other party in
writing in the event that any third party shall commence or threaten to commence
an action against Terragen or Diversa alleging that the practice of a method or
process embodied in one or more claims of Diversa Patent Rights or Terragen
Patent Rights infringes a patent of a third party. Each party shall keep the
other reasonably informed with respect to the progress of any such action from
time to time. Upon a party's reasonable request and at its expense, the other
party shall cooperate with the requesting party and its counsel with respect to
the defense of any such action against the requesting party.

                                   ARTICLE 6

                                CONFIDENTIALITY

     6.1  Definition of Confidential Information.  Confidential Information
shall mean any technical, business or other proprietary information, whether
orally or in writing, furnished by one party (the "Disclosing Party") to the
other party (the "Receiving Party) in connection with this Agreement. Such
Confidential Information shall include, without limitation, the terms of this
Agreement, Diversa Patent Rights, and Terragen Patent Rights.

     6.2  Obligations.  The Receiving Party agrees that it shall:

          (a)  Maintain all Confidential Information in strict confidence,
except that the Receiving Party may disclose or permit the disclosure of any
Confidential Information to its Affiliates, directors, officers, employees,
consultants and advisors who are obligated to maintain the confidential nature
of such Confidential Information and who need to know such Confidential
Information for the purposes set forth in this Agreement;

          (b)  Use all Confidential Information solely for the purposes set
forth in, or as permitted by, this Agreement; and

          (c)  Allow its Affiliates, directors, officers, employees, consultants
and advisors to reproduce the Confidential Information only to the extent
necessary to effect the purposes set forth in this Agreement, with all such
reproductions being considered Confidential Information.

Each Party shall be responsible for any breaches of this Section 6.2 by any of
its Affiliates, directors, officers, employees, consultants and advisors.

     6.3  Exceptions.  The obligations of the Receiving Party under Section 6.2
above shall not apply to any specific Confidential Information to the extent
that the Receiving Party can demonstrate by written record that such
Confidential Information:

          (a)  Was in the public domain prior to the time of its disclosure
under this Agreement;

                                      5.       *Confidential Treatment Requested
<PAGE>

          (b)  Entered the public domain after the time of its disclosure under
this Agreement through means other than an unauthorized disclosure resulting
from an act or omission by the Receiving Party or its Affiliates, directors,
officers, employees, consultants, advisors or agents;

          (c)  Was or is independently developed or discovered by the Receiving
Party without use of the Confidential Information;

          (d)  Is or was disclosed to the Receiving Party at any time, whether
prior to or after the time of its disclosure under this Agreement, by a third
party having no fiduciary relationship with the Disclosing Party and having no
obligation of confidentiality to the Disclosing Party with respect to such
Confidential Information; or

          (e)  Is required to be disclosed to comply with applicable laws or
regulations (such as disclosure to the SEC, the EPA, the FDA, or the United
States Patent and Trademark Office or to their foreign equivalents), or to
comply with a court or administrative order, provided that the Disclosing Party
receives prior written notice of such disclosure and that the Receiving Party
takes all reasonable and lawful actions to obtain confidential treatment for
such disclosure and, if possible, to minimize the extent of such disclosure.

     6.4  Survival of Obligations.  The obligations set forth in Sections 6.1,
6.2 and 6.3 shall remain in effect after termination or expiration of this
Agreement, until such time as the Confidential Information falls into one of the
exceptions listed in Section 6.3.

     6.5  Publicity. The parties shall issue a joint press release regarding
this Agreement, the text of which shall be subject to mutual agreement of the
parties. Except for the information disclosed in the joint press release,
neither party shall use the name of the other party or reveal the terms of this
Agreement in any publicity or advertising without the prior written approval of
the other party, except that (i) either party may use the text of a written
statement approved in advance by both parties without further approval, and (ii)
either Party shall have the right to identify the other party and to disclose
the terms of this Agreement as required by applicable securities laws or other
applicable law or regulation, provided that the receiving party takes reasonable
and lawful actions to minimize the degree of such disclosure.

                                   ARTICLE 7

                             TERM AND TERMINATION

     7.1  Diversa License Term.  The term of the licenses granted to Diversa by
Terragen pursuant to this Agreement shall expire on a country by country basis,
upon the expiration of the last to expire Valid Claim within the Terragen Patent
Rights.

     7.2  Terragen License Term.  The term of the license granted to Terragen by
Diversa pursuant to this Agreement shall expire on a country by country basis,
upon the expiration of the last to expire Valid Claim within the Diversa Patent
Rights.

     7.3  Termination Upon Material Breach.  Either party may terminate the
licenses granted to the other party under this Agreement if such other party
breaches any material term of this Agreement and does not cure such breach
within [*****] following written notice; except for non-payment of money, in
which case the cure period shall be reduced to fifteen (15) days. Any right to
terminate arising under this Section 7.3 shall be stayed until resolved under
Section 9.2 if, during the relevant cure period, the party alleged to have been
in default shall:

               (i)  have initiated arbitration in accordance with Section 9.2
below, with respect to the alleged default; and

                                    6.        *Confidential Treatment Requested
<PAGE>

               (ii) be diligently and in good faith co-operating in the prompt
resolution of such arbitration proceedings.

     7.4  Termination Upon Bankruptcy.  If either party (the "Insolvent Party")
files for protection under bankruptcy laws, makes an assignment for the benefit
of creditors, appoints or suffers appointment of a receiver or trustee over its
property, files a voluntary petition under any bankruptcy or insolvency act or
has any such petition filed against it which is not discharged within sixty (60)
days of the filing thereof, then the other party may, at its sole election upon
notice to the Insolvent Party, terminate the rights granted to the Insolvent
Party by written notice to such Insolvent Party.

     7.5  Termination upon Patent Right Lapse.  Either party may terminate the
license granted to the other party under this Agreement if the other party's
Patent Rights have lapsed, been canceled or abandoned, been admitted to be
invalid or unenforceable through reissue or disclaimer or have been declared
invalid by decision or judgment of a court of competent jurisdiction.

     7.6  Termination Upon Licensed Rights Representing Majority of Assets.
Either party may terminate the licenses granted to the other party under this
Agreement if the licenses granted to the other party under this Agreement
represent more than 50% of the total assets of the other party.

     7.7  Terragen Termination Rights [*****]. Terragen may terminate the
licenses granted to Diversa under this Agreement in the event that Diversa
[*****]. In the event the license to Diversa is terminated by Terragen pursuant
this Section 7.7, such termination will be effective upon the date of such
[*****].

     7.8  Diversa Termination Rights [*****]. Diversa may terminate the license
granted to Terragen under this Agreement in the event that Terragen [*****] In
the event the license to Terragen is terminated by Diversa pursuant this Section
7.8, such termination will be effective upon the date of such [*****] Further,
in the event Terragen [*****] without prior written approval from Diversa within
[*****] of the Effective Date, Terragen shall [*****] Diversa the [*****]
Terragen by Diversa pursuant to Section 3.1 above, within [*****] of such
[*****].

     7.9  Rights Upon Expiration. Upon expiration of the licenses granted
hereunder, neither party shall have any further rights or obligations with
respect to this Agreement in the countries with respect to which this Agreement
has then expired, except that expiration shall not relieve each party of any
obligations accruing prior to such expiration or of its obligations under
Articles 4, 5 and 6 herein. This Section 7.9 (and the sections referenced
herein) shall survive expiration of this Agreement.

     7.10 Rights Upon Termination. Upon termination of the licenses granted by
one party (the "Terminating Party") to the other party (the "Terminated Party")
under this Agreement, the licenses granted by the Terminated Party to the
Terminated Party shall remain in full force effect until expiration or
termination in accordance with this Agreement. Any termination of licenses
granted under this Agreement shall not relieve either party of any obligations
with respect to such licenses accrued prior to the date of such termination or
its obligations under Articles 4, 5 and 6 herein. This Section 7.10 (and the
sections referenced herein) shall survive termination of this Agreement.

                                      7.       *Confidential Treatment Requested
<PAGE>

                                   ARTICLE 8

           ASSIGNMENT, CHANGE OF OWNERSHIP, RIGHTS UPON DISSOLUTION

     8.1   Assignment.  Except as otherwise expressly provided herein, neither
this Agreement nor any interest hereunder shall be assignable, nor any other
obligation delegable, by either party without the prior written consent of the
other; provided, however, that (subject to sections 7.7 and 7.8 above) a Party
may assign this Agreement to any affiliate of it or to any successor by law or
by sale of all or substantially all of its assets, provided that the assigning
party shall guarantee and remain liable and responsible for the performance and
further observance of all the assigning party's duties and obligations
hereunder; provided further that, in the event of such transaction, no
intellectual property rights of any person (other than Diversa or Terragen) that
is an acquiring party shall be included in the technology licensed hereunder.
The terms and provisions of this Agreement shall be binding upon the successors
and permitted assigns of the parties. Any assignment not in accordance with this
Section 8.1 shall be void.

     8.2   Diversa Rights Upon Dissolution, Liquidation, Winding Up of Terragen.
Diversa will have a right of first option to negotiate the purchase of the
Terragen Patent Rights in the event of the dissolution, liquidation or winding
up of Terragen (an "Event") (subject to Section 9.12 hereof and to applicable
bankruptcy laws) within five (5) years of the Effective Date. Terragen will
provide prompt written notice to Diversa of any Event or proposed Event. Diversa
may exercise its option to negotiate the purchase of the Terragen Patent Rights
by providing Terragen written notice within sixty (60) days after the date of
such notice to Diversa by Terragen. If Diversa elects to exercise such option,
the parties shall negotiate in good faith with the goal of entering into a
definitive agreement within ninety (90) days after the date of Diversa's notice
to Terragen. If Diversa does not exercise such option within the sixty (60) day
option period or the parties are unable to enter into a definitive agreement
within the ninety (90) day period after Diversa's notice to Terragen that is has
exercised the option (or such longer period as the parties may mutually agree in
writing), then Terragen shall be free to sell or otherwise transfer the Terragen
Patent Rights to a third party; provided that, for a period of six months
following the end of the negotiation period, Terragen may not sell or otherwise
transfer the Terragen Patent Rights to any third party containing terms and
conditions which, in the aggregate, are more favorable to such third party than
the terms and conditions last offered to Diversa by Terragen, unless Terragen
first offers Diversa the opportunity to purchase the Terragen Patent Rights on
such terms and conditions.

                                      8.       *Confidential Treatment Requested
<PAGE>

                                   ARTICLE 9

                              GENERAL PROVISIONS

     9.1  Independent Contractors.  Terragen and Diversa shall be independent
contractors and shall not be deemed to be partners, joint venturers or each
other's agents and neither party shall have the right to act on behalf of the
other except as is expressly set forth in this Agreement.

     9.2  Arbitration. The Parties shall mutually consult in good faith in an
attempt to settle amicably in the spirit of co-operation any and all disputes
arising out of or in connection with this Agreement or questions regarding the
interpretation of the provisions hereof. All controversies or claims under this
Agreement, the enforcement or interpretation hereof, or because of an alleged
breach, default or misrepresentation under the provisions hereof that cannot be
settled amicably within [*****] from the date of notification of either party to
the other of such dispute or question, which notice shall specify the details of
such dispute or question, shall be settled by final and binding arbitration in
English, by one arbitrator appointed by the American Arbitration Association
("AAA"). If the parties cannot agree on the arbitrator to be so appointed, each
party shall be entitled to appoint one (1) arbitrator, and the [*****]
arbitrators so appointed shall agree upon a third. The arbitrator(s) shall have
the technical expertise required to understand and arbitrate the dispute. The
arbitration shall be conducted in [*****] if initiated by Terragen and in
Vancouver, British Columbia, if initiated by Diversa, in each case, in
accordance with the then-existing Commercial Arbitration Rules of the AAA.
Judgment upon the award rendered by the arbitrator(s) may be entered in any
court having jurisdiction thereof; provided, however, that the law applicable to
any controversy shall be the law of the [*****] or Federal Patent Law, as
applicable, regardless of its or any other jurisdiction's choice of law
principles. Notwithstanding the foregoing, either party may apply to any court
of competent jurisdiction for a temporary restraining order, preliminary
injunction or other interim or conservatory relief, as necessary, without breach
of this arbitration agreement and without any abridgement of the powers of the
arbitrator. In no event shall the demand for arbitration be made after the date
when institution of a legal or equitable proceeding based on such claim, dispute
or other matter in question would be barred by the applicable statute of
limitations. The costs of any arbitration, including administrative and
arbitrators' fees, shall be shared equally by the parties and each party shall
bear its own costs and attorneys' and witness' fees, provided however, that the
prevailing party, if determined by the arbitrator(s), shall be entitled to an
award against the other party in the amount of the prevailing party's costs
(including arbitration costs) and reasonable attorneys' fees.

     9.3  Entire Agreement.  This Agreement, together with the Non-Disclosure
Agreement signed by the parties dated [*****] sets forth the entire agreement
and understanding between the parties as to the subject matter hereof. There
shall be no amendments or modifications to this Agreement, except by a written
document signed by both parties.

     9.4  [*****] Law.  This Agreement shall be construed and enforced in
accordance with the laws of the State of [*****] without giving effect to its
principles of conflicts of law.

     9.5   Severability.  If any provision of this Agreement is ultimately held
to be invalid, illegal or unenforceable, the validity, legality and
enforceability of the remaining provisions shall not in any way be affected or
impaired thereby.

     9.6   No Waiver. Any delay in enforcing a party's rights under this
Agreement or any waiver as to a particular default or other matter shall not
constitute a waiver of a party's right to the future enforcement of its rights
under this Agreement.

     9.7   Notices. Any notices in writing and payments to be made provided
herein shall be deemed duly given and made if sent by courier or by certified or
registered mail, postage prepaid, to the addressees below. Either party may
change its address or its designated management representative by written notice
to the other party. The date of giving such notices and payments shall be the
date of mailing.

To Terragen:

Terragen Discovery Inc.
Suite 300
2386 East Mall
UBC Vancouver, British Columbia, Canada V6T 1Z3

Attention: Dr. Mario Thomas
           Chief Executive Officer

To Diversa Corporation:

Diversa Corporation
10665 Sorrento Valley Road
San Diego, California 92121

Attention: Dr. Jay Short
           CEO, CTO and President

     9.8   Captions.  Captions and headings are relied on for convenience only
and in no way are to be construed to define, limit or affect the construction or
interpretation hereof.

                                      9.       *Confidential Treatment Requested
<PAGE>

     9.9   Governmental Approvals. Each party shall be responsible for obtaining
all necessary governmental approvals for the development, testing, production,
distribution, sale and use of any products discovered and developed by such
party using Diversa Technology or Terragen Technology licensed hereunder, at
such party's sole expense. Each party shall have sole responsibility for any
warning labels, packaging, instructions to use, and quality control with respect
to any such product.

     9.10  Compliance With Laws and Regulations. Each party shall comply with
all United States and foreign laws, regulations, rules and orders applicable to
use of the Diversa Technology or Terragen Technology, as applicable, the
development, testing, production, distribution, export, packaging, labeling,
sales and use of products derived from the use of the Diversa Technology or
Terragen Technology, as applicable.

     9.11  No Use of Name.  Neither party shall use in advertising, promotion or
sale of products, or the provision of services using the Diversa Technology or
Terragen Technology, as applicable, any trade name, trademark, servicemark,
trade-dress or other designation, or any confusingly similar variation thereof,
of the other party, unless consented to in writing by such other party.

     9.12  Section 365(n). All licenses granted under the Agreement will be
deemed licenses of rights to intellectual property for purposes of Section
365(n) of the US Bankruptcy Code and a licensee under the Agreement will retain
and may fully exercise all of its rights and elections under the US Bankruptcy
Code.

     9.13  Counterparts. This Agreement may be executed in counterparts, each of
which, when so executed and delivered, shall be deemed to be an original, and
all of which counterparts, taken together, shall constitute one and the same
instrument.

IN WITNESS WHEREOF, the parties have executed this Agreement as of the Effective
Date.

Terragen Discovery, Inc.                     Diversa Corporation


/s/ Mario Thomas                             /s/ Jay M. Short
--------------------------------             -----------------------------------
Dr. Mario Thomas                             Dr. Jay M. Short
President                                    CEO, President and CTO

                                     10.       *Confidential Treatment Requested
<PAGE>

                                   EXHIBIT A

                             [*****] Patent Rights

Issued Patent Number/
Serial Number        Title

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

                                               *Confidential Treatment Requested
<PAGE>

                                   EXHIBIT B

                             [*****] Patent Rights

Issued Patent Number/
Serial Number        Title

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

[*****]                [*****]

                                               *Confidential Treatment Requested