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Sample Business Contracts

Consulting Agreement - CytoTherapeutics Inc. and Seth A. Rudnick

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                               CYTOTHERAPEUTICS, INC.
                           701 George Washington Highway
                                 Lincoln, RI  02865
                                   (401) 288-1000
                                         



                              Dated as of September 30, 1997




Seth A. Rudnick, M.D.
CytoTherapeutics, Inc.
701 George Washington Highway
Lincoln, RI  02865

     Re:  Board Chairman and Consulting Positions

Dear Seth:

     This letter will reflect our understanding in regard to your agreement to
serve as Chairman of the Board of Directors of CytoTherapeutics, Inc. (the
"Company") and as a Consultant to the Company. 

     1.   Change in Position and Duties.  Effective as of September 30, 1997,
          you will cease to serve as President and Chief Executive Officer of
          the Company.  You will continue to serve as Chairman of the Board of
          Directors of the Company until the next Annual Meeting of the
          Stockholders of the Company and the provisions of this Agreement
          regarding your service as Chairman of the Board shall also apply
          during any further period in which you may be elected to such
          position.  As Chairman of the Board,  you will chair all meetings of
          the Board of Directors of the Company and will have those other duties
          and responsibilities, if any, specified for the Chairman of the Board
          of Directors of the Company in the By-laws of the Company, as the same
          may exist from time to time. 

          1.1. Transition Period.  During the period commencing October 1, 1997
               through December 31, 1997 (the "Transition Period"), you will
               make yourself available as requested by the Company's Chief
               Executive Officer to fulfill such other duties and
               responsibilities as the Chief Executive Officer may reasonably
               expect, consistent with your status as




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               the current Chairman of the Board of Directors of the Company and
               former President and Chief Executive Officer of the Company and
               with any applicable provisions of this Agreement.  In this regard
               it is expected that you will devote approximately one day per
               week to in-office consultation with the Chief Executive Officer
               and other members of the Company's senior management; that you
               will travel on Company business as the Chief Executive Officer
               may reasonably request for an additional one or two days per
               week; and that you will make yourself generally available as
               required at other times during normal business hours to consult
               by telephone regarding the business of the Company. 

          1.2. Consulting Period.  From January 1, 1998 through December 31,
               1999 (the "Consulting Period"), you will serve as a Consultant to
               the Company and shall provide such consulting services to the
               Company as the Company's Chief Executive Officer may reasonably
               request from time to time up to a maximum commitment of 5 days
               per month and 50 days per year of such consulting services. 

     2.   Salary and Bonus. 

          2.1. Transition Period.  During the Transition Period, your salary
               shall be paid at an annual rate of $200,000 per year. 

          2.2. 1997 Bonuses.  The Board of Directors will review your
               performance in all positions you have held with the Company
               during 1997 and you shall be eligible to receive a bonus at least
               equal to the bonus you would have been eligible to receive under
               your employment contract as President and CEO for the time during
               1997 in which you served in such capacity (up to (9 months/12
               months) x 20% x $300,000 = $45,000). 

          2.3. Consulting Period Payments.  For your services as a Consultant
               and, to the extent applicable, Chairman and a member of the Board
               of Directors of the Company, during the Consulting Period  you
               shall be paid a consulting fee of $12,500 per month, plus
               reimbursement for any out-of-pocket expenses reasonably incurred
               by you in the course of performing such services, subject to
               appropriate documentation of such expenses on a basis consistent
               with Company policy.  During the Consulting Period you shall not
               receive any other compensation for any service you may render as
               a member of the Board of Directors of the Company or as Chairman
               thereof; should you serve in any such position after the end of
               the Consulting Period, you shall be compensated therefore
               according to the Company's then-existing policies for the
               compensation of a non-employee holding any such position.



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          2.4. Vacation Pay.  No later than January 15, 1998, you shall be paid
               $25,000 as a lump sum payment in lieu of all unused vacation time
               accrued by you during your service as Chief Executive Officer of
               the Company. 

     3.   Stock Options.  During the Transition Period and the Consulting
          Period, stock options granted to you and not yet expired, exercised,
          canceled or otherwise become unexerciseable shall continue to vest.
          In addition, subject to approval by the Company's Board of Directors,
          the exercise period for all options previously granted to you shall be
          extended until the end of the Consulting Period (i.e., all options may
          be exercised at any time prior to December 31, 1999 and must be
          exercised no later than that date).

     4.   Benefits. 

          4.1. Health and Dental.  During the Transition Period and the
               Consulting Period, to the extent permitted by the terms of the
               Company's group health and dental plan and by its health and
               dental plan insurer or providers, as applicable, the Company will
               continue your participation and that of your eligible dependents
               in its group health and dental plan to the same extent as you and
               they currently participate and will pay the premium cost of such
               participation, to the same extent currently paid, through the
               earlier of (i) the end of the Consulting Period or (ii) the date
               you commence other employment which makes you eligible, at no
               greater cost to you than the current cost to you, if any, under
               the Company's health and dental plans, to obtain comparable
               coverage under the health and dental plans of your new employer.
               If the Company is unable to provide continuation as contemplated
               in the previous sentence, you may exercise your right to continue
               your coverage and that of your eligible dependents in the
               Company's group health and dental plan under the federal law
               known as COBRA, provided you are eligible to do so, and, if you
               are eligible, then, until the end of the Consulting Period or the
               date you cease to be eligible for continuation under COBRA, the
               Company will pay the premium cost of your coverage and that of
               your eligible dependents. 

          4.2. Life Insurance.  During the Transition Period and the Consulting
               Period, to the extent permitted by the terms of the Company's
               group life insurance plan, the Company will continue your
               coverage under its group life insurance plan in the same face
               amount in which your life is currently insured under such plan
               through the end of the earlier of (i) the Consulting Period or
               (ii) the date you commence other employment


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               under circumstances which entitle you to group life insurance
               coverage comparable to that provided by Company at no greater
               cost to you than such coverage as currently provided to you by
               the Company.  If life insurance coverage is not available under
               the Company's plan, the Company shall pay $2,500 per year toward
               the cost of any life insurance coverage which you may arrange.

          4.3. Plan Limitations.  It is understood and agreed that the benefits
               of the group health and group life insurance plans of the Company
               are subject to such conditions and limitations as are set forth
               in the applicable plan, policy or contract terms, as such may
               exist from time to time, and that any disputes concerning
               eligibility for payment of benefits under such plan shall be
               settled in accordance with the terms thereof, and that the
               Company shall have no liability to you, your dependents or any
               other person claiming through you, for payment of benefits under
               any such plan. 

          4.4. Retirement Annuity.  Commencing at the time you reach age 60 and
               continuing until your death, the Company shall pay to you a
               monthly retirement payment at the rate of $30,000 per year.  You
               acknowledge that this payment obligation is an unsecured payment
               obligation of the Company that has not been (and is not expected
               to be) funded by the Company through the purchase of an annuity
               contract or otherwise.

          4.5. Office Space.  During the time you serve as Chairman of the Board
               of the Company, the Company shall make available to you office
               space, either at the Company, or at the Company's option, at a
               separate location located no more than one-half hour from the
               Company, for you to use.  If the Company elects to provide you
               with a separate office location, the cost to the Company
               (including rent, secretarial services, leased equipment, etc.)
               shall not exceed $2,000 per month. 

     5.   During the Transition and Consulting Periods and for one year
          thereafter, you will not, either directly or indirectly, become
          employed by, serve as a director of or consultant to or otherwise
          participate in any competitor of the Company.  A competitor shall be
          defined as any entity utilizing or proposing to utilize the
          transplantation of cells as a therapeutic agent for the treatment of
          human disease.  You further agree that during the Transition and
          Consulting Periods and for a period of one year thereafter, you will
          not directly or indirectly solicit the services of any employee of the
          Company for another entity, or otherwise induce or attempt to induce
          any such employee to leave the employ of the Company. 

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     6.   You shall not disclose to any other person, corporation or other
          entity (except as required by applicable law or for the proper
          performance of your duties and responsibilities hereunder), or use
          for your own benefit or gain, any Confidential Information of the
          Company. Confidential Information of the Company shall mean all
          information of or regarding the Company other than information that
          is generally known to the public through no fault of yours,
          including, without limitation, information regarding the research
          and development activities of the Company, the products and
          services of the Company, the cost, sources of supply and strategic
          plans of the Company, the identity and special needs of the
          customers of the Company and those persons and organizations with
          whom the Company has business relationships and the nature of those
          relationships, as well as any comparable information that the
          Company may possess regarding customers or others who do business
          with the Company. 

     If the terms of this Letter Agreement accurately reflect your
understanding of the matters set forth herein, please sign this Agreement and
return it to the Company.  The enclosed copy of this Letter Agreement, which
you should also sign and date, is for your records.

                              Sincerely,

                              CYTOTHERAPEUTICS, INC.



                              By:___________________________
                              Name:
                              Title:



Accepted and Agreed:



     /s/ Seth Rudnick
---------------------------
Seth A. Rudnick, M.D.


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